Hashimoto’s Disease

A Educational Hand-Out

Hashimoto’s—a autoimmune disease in which organs are attacked by a variety of cells-and antibodys-mediated process

Hashimoto’s thyroiditis---(chronic lymphocytic thyroiditis) is an autoimmune disease in which the thyroid gland is attacked by a variety of cell- and antibody mediated immune processes

Autoimmune thyroiditis---(chronic autoimmune thyroiditis) a disease in which the body interprets the thyroid glands and its hormone products t3,t4 and TSH as threats therefore produceing special antibodies that target the thyroid’s cells thereby destroying it

The thyroid—releases hormones that help metabolism,body temperature,muscle strength and help keep your organs running

Hashimoto’s—Develops when the immune system attacks the thyroid gland, It may be related to such hormone-related(endocrine system) disorder as: 1. Addison diseases 2. Diabetes mellitus 3. Graves disease 4. Vitiligo

Hashimoto’s—Also known as: 1. Autoimmune thyroiditis 2. Chronic lymphocytic thyroiditis 3. Lymphadenoid goiter
4. Stuma lymphomatosa

Hashimoto’s signs and symptoms--- some signs may be: 1. Constipation 2. Fatigue 3. goiter or enlarged neck
4. inability to tolerate cold temperatures 5. High Cholesterol 6. weight gain 7. face swelling 8. joint stiffness or muscle weakness,muscle cramps 9. thinning hair 10. hoarse voice 11. excessive/prolonged menstrual bleeding 12. Depression

Hashimoto’s---some cases of hashimoto’s disease remain stable for years,others slowly progress to hypothyroiditism which is treated with thyroid hormone replacement therapy

Causes of Hashimoto’s—Many causes but, here are some: 1. Genes 2. Iodine 3. Some drugs may trigger the onset of thyroid diseases in people prone to getting it 4. Radiation 5. Medications and psychiatric medications (lithium,valproate and many others.(some medicines and psychiatric medicines cause thyroid problems and diseases)

What would happen or could happen if hashimoto’s was not treated: progress and symptoms can get worse, an untreated underactive thyroid can cause high cholesterol, infertility, miscarriage,birth defects, Severe underactive thyroid called myxedema can( very rarely) lead to heart failure,seizures,coma,death

Other Terms

Riedel’s thyroiditis—in which scar tissues progresses in the thyroid until it produces a hard stony mass that suggests cancer hypothyroidism develops as the scar tissue replaces healthy tissue, chronic type of autoimmune thyroiditis with a proliferating,fibrosing,inflammatory process involveing usually one but, sometimes both lobes of the gland which become hard and enlarged and adherent to the trachea and other adjacent structures (called also riedels struma)

Granulomatous—giant cell thyroiditis-thyroid inflammation-a mass of inflamed tissue immune disorder, immune disorder that occurs when a type of white blood cell (phagocyte) that usually help your body fight infections doesn’t work properly

Atrophic thyroiditis—is a fancy medical term for inflammation of the thyroid due to autoimmune hashimoto’s disease
A type of autoimmune thyroiditis with a atrophy of follicles and without goiters or replacement of the thyroid gland by fibrous tissue

Goiter—abnormally enlarged thyroid gland
Page Two of Hashimoto’s

Atrophy—a wasteing away of an organ or part or decrease in size of organ or tissue which was once fully developed and normal size

Atrophic—related to or characterized by atrophy

Information taken from: internet
www.en.wikipedia.org
www.google.com
www.health.harvard.edu/fhq/updates/thyroid-deficiency-and-mental health.shtml
www.nytimes.com/health/guides/diseases/chronic-thyroiditis-hashimoto’s-disease/causes.html
www.update.com
www.womenshealth.gov

Information taken also from library books about the thyroid and books on pharmaceutical books on medications and medical books

IF you feel a medicine you have started or been started on may have caused you a thyroid problem or a other medical problem make sure to tell your doctor that you feel a medicine may have caused your medical problem and if you did not have a medical problem diagnosed with prior to starting a medicine and came down with it and diagnosed with it after starting a medicine and feel it was or may be the cause of medical condition let your doctor know that right away

Written by
Katrine Sackett 32463 whitelady 5’3 -----521/2
7101 n ih 35 austin tx apt 214
________________________________________________________________________
HYPOTHYROIDISM

A Educational Hand-out

Hypothyroidism—Also known as (underactive thyroid or low thyroid and hypothyreosis) is when the thyroid does not produce enough thyroid hormones

Subclinical Hypothyroidism-- is a milder form of hypothyroidism characterized by normal thyroxine levels and an elevated TSH level

Thyroid hormones is required for the normal functioning of numerous tissues and body organs in the body the thyroid gland predominantly secrets thyroxine (t4) which is converted into triiodothyronine(t3) in other organs by the selenium-dependent enzyme iodothyronine deiodinase, Triiodothyronine binds to the thyroid hormone receptor in the cells were it stimulates the turning on of particular genes and the production of specific proteins Additionally, the hormones binds to integrin AVB3 on the cell membrane thereby stimulating the sodium-hydrogen antiportor and processes such as formation of blood vessels and cell growth. In blood almost all thyroid hormone is bound to plasma proteins such as thyroxine-binding globulin only the free unbound thyroid hormone is biologically active. The thyroid gland is only source of the thyroid hormone in the body the process requires iodine and amino acid tyrosine, Iodine in the bloodstream is taken up by the gland and incorporated into thyroglobulin molecules and the process is controlled by the thyroid stimulating hormone(TSH,Thyrotropin) which is secreted by the pituitary, not enough iodine or not enough TSH can result in decreased production of thyroid hormones.(tg)

(The hypothalamus secrets TRH which stimulates the production of TSH by the pituitary gland this in turn stimulates the production of thyroxine by the thyroid, thyroxine levels decrease TRH and TSH production by negative feedback process)

The hypothalamic-pituitary-thyroid axis plays a key role in maintaining thyroid hormone levels within normal limits, production of TSH by the anterior pituitary gland is stimulated in turn by thyrotropin-releaseing hormone(TRH) released from the hypothalamus, production of TSH and TRH is decreased by thyroxine by negative feedback process not enough TRH (which is uncommon) can lead to not enough TSH and thereby to not enough thyroid hormone production.

Pregnant – leads to marked changes in thyroid hormones physiology, many women have normal thyroid function but, have immunological evidence of thyroid autoimmunity (as evidenced by autoantibodies) or are iodine deficient and develop evidence of hypothyroidism before or after birth.

Hypothyroidism signs and symptoms--- many but, here are a few –fatigue,feeling cold, dry/coarse skin, poor hearing.

Hypothyroidism caused by ----many but, here are a few--- injury to the hypothalamus or anterior pituitary gland, not enough iodine or damaged by medications like lithium or valproax

Other Terms

Overt primary hypothyroidism---is when TSH levels are high and t4 and t3 levels are low

Myxedema coma or severe decompensated hypothyroidism---- usually require admission to intensive care

Hypopituitarism----is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain, If there is decreased secretion of most pituitary hormones the term panhypopituitarism is used (pan-meaning all) and the signs and symptoms very depending on which hormones are undersecreted and on the underlying cause of abnormality

Hyperthyroidism----(overactive thyroid) a condition which the thyroid gland produces and secrets excessive (to much)amount of the free (not protein bound circulating in the blood) thyroid hormone(triiodothyronine t3 and/or thyroxine t4)

If you believe/feel a medication you started on has caused you a medical condition which you did not have before you started the medicine but were diagnosed with it after you started the medicine and feel a medicine caused the disease tell your doctor

Written by Katrine Sackett 32463 whitelady 5’3--------5’21/2 7101 n ih 35 austin tx by burger king

Information taken from internet articles and en.wikipedia.org and library books

TRH FREE ACID
THYROLIBERIN---PROTIRELIN
TRIPEPTIDAL---PROLACTIN
TSH OR HTSH-EUTHYROID SICK SYNDROME
SUBACUTE THYROIDITIS (SAT)
SUBPOTENT HORMONES B(BETA) HASHITOXICOSIS
TSHB
GESTATIONAL HYPERTHYROIDISM
CONGENTITAL(CH) –CRETINISM---PRIMARY HYPOTHYROIDISM I.E. HASHIMOTO’S ATHYREOSIS
ECTOPIC SPORADIC
LINGUAL THYROID
PEJORATIVE CONNOTATIONS
EXTRACELLULAR LIGAND DISORDER
CATECHOLAMINE EFFECT
ULTRA-SOUND WITH DOPLER –USEFUL TEST ANTIBODY
NEGATIVE FEEDBACK CONTRIBUTES TO THE BODYS ABILITY TO MAINTAIN A APPROPRIATE LEVEL OF THYROID HORMONES
THYROID-STIMULATEING HORMONES RECEPTOR (TSHR)

from Katrine sackett32463whitelady (5'3)(5'21/2)
the information was taken/came from library books (medical)
and internet articles
today is feb 26 2019 10pm

Views: 
1813
Post type: 
Author: 
lizWALD
Address: 
United States