Invega Sustenna
Generic drug name: Paliperidone
This medication is used to treat certain mental/mood disorders.

Side Effects


Pregnancy category: Consult a doctor
Availability: Prescription needed
Drug classes: Antipsychotic · Atypical antipsychotic
Other brand names: Invega · Invega Trinza
May treat: Schizophrenia · Schizoaffective disorder
Consult a medical professional for advice.
Data from: First Databank · Freebase
Suggest an edit

o Official Site | INVEGA SUSTENNA®

Ad(paliperidone palmitate) - Find Helpful Product Info Including, Boxed Warning.
2. Invega Sustenna side effects (intramuscular)
Tell your doctor right away if you have any serious side effects, including:
• Difficulty swallowing
• Restlessness
• Muscle spasms
• Interrupted breathing during sleep
Get medical help right away if any of these rare but serious side effects occur:
• Fainting
• Severe dizziness
• Slow heartbeat
• Seizures
This medication may rarely cause a very serious condition called neuroleptic malignant syndrome . Get medical help right away if you have any of the following symptoms:
• Fever
• Muscle stiffness/pain/tenderness/weakness
• Severe tiredness
• Severe confusion
• Sweating
• Fast/irregular heartbeat
• Dark urine
• Signs of kidney problems
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
• Fever
• Swollen lymph nodes
• Rash
• Itching/swelling
• Severe dizziness
• Trouble breathing
Other things to note:
• Drowsiness, dizziness, lightheadedness, weight gain, or pain/redness/swelling at the injection site may occur. If any of these side effects persist or worsen, tell your doctor promptly.
• Dizziness and lightheadedness can increase the risk of falling. These effects are more likely to occur in the first few days after starting/restarting the drug or after your dose increases. Get up slowly when rising from a sitting or lying position.
• Paliperidone may rarely cause a condition known as tardive dyskinesia. In some cases, this condition may be permanent. Tell your doctor right away if you develop any unusual/uncontrolled movements .
• This drug may rarely make your blood sugar rise, which can cause or worsen diabetes. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
• This drug may also cause significant weight gain and a rise in your blood cholesterol levels. These effects, along with diabetes, may increase your risk for developing heart disease. Discuss the risks and benefits of treatment with your doctor.
• Rarely, this medication may increase your blood level of a certain hormone . In females, an increase in prolactin levels may result in unwanted breast milk, missed/stopped periods, or difficulty becoming pregnant. In males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. If you develop any of these symptoms, tell your doctor right away.
• For males, in the very unlikely event you have a painful or prolonged erection , stop using this drug and seek immediate medical attention, or permanent problems could occur.
Data from: First DataBank · Consult a medical professional for advice.

INVEGA SUSTENNA® may cause serious side effects, including:
• See “What is the most important information I should know about INVEGA SUSTENNA®?”
• stroke in elderly people (cerebrovascular problems) that can lead to death
• Neuroleptic Malignant Syndrome (NMS). NMS is a rare but very serious problem that can happen in people who receive INVEGA SUSTENNA®. NMS can cause death and must be treated in a hospital. Call your healthcare professional right away if you become severely ill and have any of these symptoms: high fever; severe muscle stiffness; confusion; loss of consciousness; changes in your breathing, heartbeat, and blood pressure
• problems with your heartbeat. These heart problems can cause death. Call your healthcare professional right away if you have any of these symptoms: passing out or feeling like you will pass out; dizziness; or feeling as if your heart is pounding or missing beats
• uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia)
• metabolic changes. Metabolic changes may include high blood sugar (hyperglycemia), diabetes mellitus and changes in the fat levels in your blood (dyslipidemia), and weight gain
• low blood pressure and fainting
• changes in your blood cell counts
• high level of prolactin in your blood (hyperprolactinemia). INVEGA SUSTENNA® may cause a rise in the blood levels of a hormone called prolactin (hyperprolactinemia) that may cause side effects including missed menstrual periods, leakage of milk from the breasts, development of breasts in men, or problems with erection
• problems thinking clearly and moving your body
• seizures
• difficulty swallowing that can cause food or liquid to get into your lungs
• prolonged or painful erection lasting more than 4 hours. Call your healthcare professional or go to your nearest emergency room right away if you have an erection that lasts more than 4 hours
• problems with control of your body temperature, especially when you exercise a lot or spend time doing things that make you warm. It is important for you to drink water to avoid dehydration
The most common side effects of INVEGA SUSTENNA® include: injection site reactions; sleepiness or drowsiness; dizziness; feeling restlessness or needing to be constantly moving; abnormal muscle movements, including tremor (shaking), shuffling, uncontrolled involuntary movements, and abnormal movements of your eyes.
Tell your healthcare professional if you have any side effect that bothers you or does not go away. These are not all the possible side effects of INVEGA SUSTENNA®. For more information, ask your healthcare professional or pharmacist.
Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit, or call 1 800 FDA 1088.

© Janssen Pharmaceuticals, Inc. 2018. All rights reserved.
This site is published by Janssen Pharmaceuticals, Inc., which is solely responsible for its contents. The material on this site is intended only as informational or as an educational aid and it is not intended to be taken as medical advice. The ultimate responsibility for patient care resides with a healthcare professional.
This information is intended for the use of patients and caregivers in the United States and Puerto Rico only. Laws, regulatory requirements, and medical practices for pharmaceutical products vary from country to country. The Prescribing Information included here may not be appropriate for use outside the United States and Puerto Rico.
Capitalized product names are trademarks of Janssen Pharmaceuticals, Inc.
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Last updated October 19, 2018

difficulty swallowing that can cause food or liquid to get into your lungs
metabolic changes. Metabolic changes may include high blood sugar (hyperglycemia), diabetes mellitus and changes in the fat levels inproblems with your heartbeat. These heart problems can cause death. Call your healthcare professional right away if you have any of these symptoms: passing out or feeling like you will pass out; dizziness; or feeling as if your heart is pounding or missing beats your blood (dyslipidemia), and weight gain

NVEGA TRINZA ® (3-month paliperidone palmitate) is a prescription medicine given by injection every 3 months by a healthcare professional and used to treat schizophrenia. INVEGA TRINZA ® is used in people who have been treated with INVEGA SUSTENNA ® (1-month paliperidone palmitate) for at least 4 months. INVEGA SUSTENNA ® (In-VEY-guh Suss-TEN-uh) (paliperidone palmitate) is a prescription medicine given by injection by a healthcare professional. INVEGA SUSTENNA ® is used to treat schizophrenia in adults.
INVEGA TRINZA® (paliperidone palmitate) | Homepage

INVEGA® can cause serious side effects, including an increased risk of death in elderly people who are confused, have memory loss and have lost touch with reality (dementia-related psychosis). INVEGA® is not for treating dementia-related psychosis.
Do not receive INVEGA® if you are allergic to paliperidone, risperidone, or any of the ingredients in INVEGA®.
Cerebrovascular problems (stroke) that can lead to death have been reported in elderly patients with dementia-related psychosis.
Neuroleptic Malignant Syndrome (NMS) is a rare but very serious problem that can happen in people who receive INVEGA®. NMS can cause death and must be treated in a hospital. Call your healthcare professional right away if you become severely ill and have any of these symptoms: high fever, severe muscle stiffness, confusion, loss of consciousness, or changes in your breathing, heartbeat and blood pressure.
Tardive Dyskinesia (TD) is a serious, sometimes permanent side effect reported with INVEGA® and similar medications. TD includes uncontrollable movements of the face, tongue, and other parts of the body. The risk of developing TD and the chance that it will become permanent

INVEGA® (paliperidone) is used for the short-term treatment of schizoaffective disorder in adults and for the treatment of schizophrenia in adults.

having to urinate or “pass urine” more often than usual, or feeling weak or hungry

This medicine may make you more sensitive to heat. You may have trouble cooling off or be more likely to become dehydrated. Be careful when you exercise or spend time doing things that make you warm.

The most common side effects that occurred with INVEGA® in the treatment of schizoaffective disorder in adults were: abnormal muscle movements (including tremor [shaking]), shuffling, uncontrolled involuntary movements, and abnormal movements of the eyes), sleepiness, heartburn, constipation, weight increase, and sore throat

he most common side effects observed in clinical trials for the treatment of schizoaffective disorder were: abnormal muscle movements (including tremor [shaking], shuffling, uncontrolled involuntary movements, and abnormal movements of the eyes), heartburn, constipation, sleepiness, weight increase, and sore throat.

What are the psychotic symptoms of schizoaffective disorder?
When people with schizoaffective disorder experience psychotic symptoms, they can include:
• Seeing, hearing, or sensing things that are not there (hallucinations)
• Believing that what other people say is not true (delusions)
• Not trusting others and feeling very suspicious (paranoia)
• Avoiding family and friends and wanting to be alone
• Being less able to show feelings
• Being less able to speak or think clearly
• Losing an interest in or ability to do tasks or activities
What are the mood symptoms of schizoaffective disorder?
People with the depressive subtype of schizoaffective disorder exclusively experience depressive episodes, which include:
• Feelings of sadness or emptiness
• Tearfulness
• Weight loss or change in appetite
• Too little or too much sleep
• Restlessness
• Feeling tired or lack of energy
• Guilt or self-blame
• Loss of concentration or the ability to make decisions
• Loss of interest or pleasure in activities that were once enjoyed
• Thoughts of death or suicide
People with the bipolar subtype of schizoaffective disorder experience manic or mixed episodes (and may or may not also experience depressive episodes). Manic mood symptoms include:
• Unusually high, grand, or irritable mood
• Inflated self-esteem
• Decreased need for sleep
• More talkative than usual
• Racing thoughts or ideas
• Easily distracted
• An increase in working towards goals (especially in creative work)
• Risky behavior (such as gambling or sex with many partners)

What is schizoaffective disorder?
Schizoaffective disorder is a life-long mental health condition. Some symptoms of schizoaffective disorder can affect:
• Your ability to think clearly
• How you relate to others
• How you express your emotions
Schizoaffective disorder is a distinct mental disorder. Often people who have it have been diagnosed with other mental illnesses in the past because its symptoms can be similar to schizophrenia, depression, or bipolar disorder.
Schizoaffective disorder can be difficult to diagnose. That’s why it’s important and helpful to discuss with your doctor your symptoms, thoughts, feelings, and how they change over time. Talking about your experiences with your treatment team may help them create a better treatment plan for you.
According to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, schizoaffective disorder is defined by the following:
• Periods when psychotic symptoms and
mood symptoms (like mania, depression) occur at the same time
• At least 2 weeks of hallucinations and delusions without any mood symptoms
• You experience mood symptoms for a majority of the time
• Symptoms are not due to substance abuse, medication, or a general medical issue
• NVEGA® (paliperidone) extended-release tablets are indicated for the treatment of schizophrenia in adults and adolescents (12-17 years of age). The efficacy of INVEGA® in schizophrenia was established in three 6-week trials in adults and one 6-week trial in adolescents (12-17 years of age), as well as one maintenance trial in adults.
• INVEGA® (paliperidone) extended-release tablets are indicated for the treatment of schizoaffective disorder as monotherapy and as an adjunct to mood stabilizers and/or antidepressant therapy in adults. The efficacy of INVEGA® in schizoaffective disorder was established in two 6-week trials in adults.

Death is found among people who take Invega, especially for people who are male, 40-49 old , have been taking the drug for < 1 month, also take medication Risperdal, and have Depression. This study is created by eHealthMe based on reports of 27,385 people who have side effects when taking Invega from FDA, and is updated regularly.

Invega has active ingredients of paliperidone. It is often used in bipolar disorder. (latest outcomes from Invega 27,715 users)
What is Death?
Death has been reported by people with multiple myeloma, primary pulmonary hypertension, pain, chronic myeloid leukaemia, diabetes (latest reports from 484,550 Death patients).

What would you like to know about paliperidone?
paliperidone injectionside effects for paliperidonepaliperidone brand name

1. Paliperidone: Uses vs Side Effects
Paliperidone , sold under the trade name Invega among others, is a dopamine antagonist and 5-HT 2A antagonist of the atypical antipsychotic class of medications. It is marketed by Janssen Pharmaceutica . Invega is an extended release formulation of paliperidone that uses the OROS extended release system to allow for once-daily dosing. Paliperidone is mainly used to treat schizophrenia and schizoaffective disorder . It is also used to treat mania and at lower doses as maintenance for bipolar disorder .
Paliperidone - Wikipedia
In Summary. Commonly reported side effects of paliperidone include: akathisia, tachycardia, and drowsiness. Other side effects include: basal ganglia disease, dyskinesia, dystonia, orthostatic hypotension, postencephalitic parkinson's disease, sialorrhea, and prolonged qt interval on ecg.
Paliperidone Side Effects in Detail -

A study for a 32 year old woman who takes Synthroid - from FDA reports

11,688 females aged 32 (±5) who take the same drug are studied. This is a personalized study for a 32 year old female patient who has Hypothyroidism. The study is created by eHealthMe based on reports from FDA.
How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

Peer to Peer mobile support
Peer support for this study is available on our Ginger Health app. It's free, anonymous and secure. The app is ideal for people taking multiple medications or having multiple conditions.

On Mar, 09, 2019
11,688 females aged 32 (±5) who take Synthroid are studied.
Number of reports submitted per year:

Information of the patient in this study:
• Age: 32
• Gender: female
• Conditions: Hypothyroidism
• Drugs taken:
o Synthroid (levothyroxine sodium)
eHealthMe real world results:
Comparison with this patient's adverse outcomes:
• Nipple Discharge - Abnormal: 0 (0% of females aged 32 (±5) who take the drug)

As an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea
• Nipple Discharge - Abnormal in Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 0 (0% of females aged 32 (±5) who have Hypothyroidism)

As an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea
• Nipple Discharge - Abnormal in Synthroid: 0 (0% of females aged 32 (±5) who take Synthroid)

Most common side effects over time
< 1 month:
1. Nausea (feeling of having an urge to vomit)
2. Heart palpitations (feelings or sensations that your heart is pounding or racing)
3. Arrhythmias (irregular heartbeat)
4. Rashes (redness)
5. Weight increased
6. Insomnia (sleeplessness)
7. Malaise (a feeling of general discomfort or uneasiness)
8. Weakness
9. Feeling abnormal
10. Tremor (trembling or shaking movements in one or more parts of your body)
1 - 6 months:
1. Fatigue (feeling of tiredness)
2. Dizziness
3. Headache (pain in head)
4. Insomnia (sleeplessness)
5. Nausea (feeling of having an urge to vomit)
6. Stress and anxiety
7. Heart palpitations (feelings or sensations that your heart is pounding or racing)
8. Blood thyroid stimulating hormone increased
9. Weight increased
10. Breathing difficulty
6 - 12 months:
1. Fatigue (feeling of tiredness)
2. Headache (pain in head)
3. Dizziness
4. Nausea (feeling of having an urge to vomit)
5. Weakness
6. Weight increased
7. Maternal exposure during pregnancy (use of substance during pregnancy)
8. Depression
9. Hair loss
10. Insomnia (sleeplessness)
1 - 2 years:
1. Fatigue (feeling of tiredness)
2. Weight increased
3. Blood thyroid stimulating hormone increased
4. Insomnia (sleeplessness)
5. Dizziness
6. Depression
7. Breathing difficulty
8. Nausea (feeling of having an urge to vomit)
9. Rashes (redness)
10. Weakness
2 - 5 years:
1. Injury
2. Pain
3. Emotional distress
4. Fatigue (feeling of tiredness)
5. Stress and anxiety
6. Abortion spontaneous (naturally occurring miscarriage)
7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
8. Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
9. Loss of consciousness
10. Heart palpitations (feelings or sensations that your heart is pounding or racing)
5 - 10 years:
1. Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
2. Stress and anxiety
3. Pulmonary embolism (blockage of the main artery of the lung)
4. Pain in extremity
5. Pain
6. Fatigue (feeling of tiredness)
7. Depression
8. Oedema peripheral (superficial swelling)
9. Weight increased
10. Injury
10+ years:
1. Stress and anxiety
2. Pulmonary embolism (blockage of the main artery of the lung)
3. Blood thyroid stimulating hormone increased
4. Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
5. Breathing difficulty
6. Hair loss
7. Emotional distress
8. Dizziness
9. Nausea (feeling of having an urge to vomit)
10. Injury
not specified:
1. Fatigue (feeling of tiredness)
2. Nausea (feeling of having an urge to vomit)
3. Headache (pain in head)
4. Dizziness
5. Pain
6. Stress and anxiety
7. Depression
8. Weakness
9. Nausea and vomiting
10. Breathing difficulty
Top conditions involved for these people *:
1. Birth Control : 1,205 people, 10.31%
2. Depression : 849 people, 7.26%
3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 480 people, 4.11%
4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 440 people, 3.76%
5. Pain : 435 people, 3.72%
6. Stress And Anxiety : 420 people, 3.59%
7. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 335 people, 2.87%
8. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 330 people, 2.82%
9. Migraine (headache): 301 people, 2.58%
10. High Blood Pressure : 297 people, 2.54%
Top co-used drugs for these people *:
1. Yasmin (727 people, 6.22%)
2. Humira (644 people, 5.51%)
3. Yaz (551 people, 4.71%)
4. Zoloft (428 people, 3.66%)
5. Cymbalta (370 people, 3.17%)
6. Topamax (356 people, 3.05%)
7. Lexapro (338 people, 2.89%)
8. Nexium (327 people, 2.80%)
9. Prednisone (327 people, 2.80%)
10. Xanax (324 people, 2.77%)
* Some reports may have incomplete information.
You are not alone:
• Connect with people like you who take the same medications and have the same conditions
• Use your healthcare experience to help people like you, and be rewarded
What are the drugs?
• Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 170,727 users)
What are the conditions?
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) can be treated by Synthroid, Levothyroxine sodium, Levothyroxine thyroid, Levoxyl, Levothroid (latest reports from 104,371 Hypothyroidism patients)
What are the symtoms?
• Nipple discharge - abnormal has been reported by people with attention deficit hyperactivity disorder, depression, bipolar disorder, psychotic disorder, stress and anxiety (latest reports from 106 Nipple discharge - abnormal patients).
Could your drugs cause:
• Nipple discharge - abnormal
Could your conditions cause:
• Nipple discharge - abnormal
Related studies:
• Synthroid side effects (161,675 reports)
Related publications that referenced our studies
• Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
FDA reports used in this study
• Want to find out more about the FDA reports used in the study? You can request them from FDA.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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Clinical data
Trade names
Invega, Xeplion, others
Synonyms 9-hydroxyrisperidone


License data
• EU EMA: by INN
• US FDA: Paliperidone

• AU: B3
• US: C (Risk not ruled out)

Routes of
Oral (OROS tablets), IM depot injection

ATC code
• N05AX13 (WHO)

Legal status
Legal status
• AU: S4 (Prescription only)
• US: ℞-only

Pharmacokinetic data

28% (oral)
Elimination half-life
23 hours (by mouth)
1% unchanged in urine 18% unchanged in feces
IUPAC name[show]

CAS Number
• 144598-75-4

PubChem CID
• 115237

• DB01267

• 7978307

• 838F01T721

• D05339

• CHEBI:82978

• ChEMBL1621

ECHA InfoCard

Chemical and physical data
Molar mass
426.484 g/mol g·mol−1
3D model (JSmol)
• Interactive image



(what is this?) (verify)

Paliperidone, sold under the brand name Invega among others, is an atypical antipsychotic. It is marketed by Janssen Pharmaceutica. Invega is an extended release formulation of paliperidone that uses the OROS extended release system to allow for once-daily dosing. Paliperidone is mainly used to treat schizophrenia and schizoaffective disorder.
Paliperidone palmitate is a long-acting injectable formulation of paliperidone palmitoyl ester indicated for once-every 28 days injection after an initial titration period.

• 1Medical use
• 2Adverse effects
o 2.1Deaths
• 3Pharmacology
• 4History
• 5Brand names
• 6References
• 7External links
Medical use[edit]
It is used for the treatment of schizophrenia and schizoaffective disorder. In a 2013 study in a comparison of 15 antipsychotic drugs in effectiveness in treating schizophrenic symptoms, paliperidone was ranked fifth and demonstrated standard-high effectiveness. 10-14% more effective than haloperidol, quetiapine, and aripiprazole, 11% less effective than risperidone (4th), and 43% less effective than clozapine (1st).[1]
Paliperidone palmitate long-acting injection compared to risperidone for schizophrenia[2]

When flexibly dosed every four weeks, paliperidone palmitate appears comparable in efficacy and tolerability to risperidone. In short-term studies, paliperidone palmitate - the longer-acting injection - has a similar adverse effect profile to related compounds such as risperidone by mouth. No difference was found in the high rate of reported adverse sexual outcomes and paliperidone palmitate is associated with an increase in serum prolactin.[2]

showOutcome Findings in words Findings in numbers Quality of evidence

Adverse effects[edit]
Very Common (>10% incidence)
• Headache
• Tachycardia
• Somnolence (causes less sedation than most atypical antipsychotics)[1]
• Insomnia
• Hyperprolactinaemia (seems to cause comparable prolactin elevation to its parent drug, risperidone)[1]
• Sexual Dysfunction
Common (1–10% incidence)
• Cough
• Extrapyramidal side effects (EPSE; e.g. dystonia, akathisia, muscle rigidity, parkinsonism. It appears to produce similar EPSE to risperidone, asenapine and ziprasidone and more EPSE than olanzapine, clozapine, aripiprazole, quetiapine, amisulpride and sertindole)[1]
• Orthostatic hypotension
• Weight gain (tends to produce a moderate degree of weight gain, possibly related to its potent blockade of the 5-HT2C receptor)
• QT interval prolongation (tends to produce less QT interval prolongation than most other atypical antipsychotics and approximately as much QT interval prolongation as aripiprazole and lurasidone)[1]
• Nasopharyngitis
• Anxiety
• Indigestion
• Constipation
In April 2014, it was reported that 21 Japanese people who had received shots of the long-acting injectable paliperidone to date had died, out of 10,700 individuals prescribed the drug.[8][9][10][11][12][13][14]

Site Ki (nM)
Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site.
Paliperidone is the primary active metabolite of the older antipsychotic risperidone.[16] While its specific mechanism of action is unknown, it is believed paliperidone and risperidone act via similar, if not identical, pathways.[17] Its efficacy is believed to result from central dopaminergic and serotonergic antagonism. Food is known to increase the absorption of Invega type ER OROS prolonged-release tablets. Food increased exposure of paliperidone by up to 50-60%, however, half-life was not significantly affected. The effect was probably due to a delay in the transit of the ER OROS formulation in the upper part of the GI channel, resulting in increased absorption.[18]
The half-life is 24 hours.[18]
Paliperidone (as Invega) was approved by the Food and Drug Administration (FDA) for the treatment of schizophrenia in 2006. Paliperidone was approved by the FDA for the treatment of schizoaffective disorder in 2009. The long-acting injectable form of paliperidone, marketed as Invega Sustenna in U.S. and Xeplion in Europe, was approved by the FDA on July 31, 2009. It is the only available brand in Bangladesh under the brand name "Palimax ER" manufactured & marketed by ACI Pharmaceuticals.
It was initially approved in Europe in 2007 for schizophrenia, the extended release form and use for schizoaffective disorder were approved in Europe in 2010, and extension to use in adolescents older than 15 years old was approved in 2014.[19]
Brand names[edit]
On May 18, 2015, a new formulation of paliperidone palmitate was approved by the FDA under the brand name Invega Trinza.[20] A similar 3 -monthly injection of prolonged release suspension was approved in 2016 by the European Medicines Agency originally under the brand name Paliperidone Janssen, later renamed to Trevicta.[21]

Antipsychotics, also known as neuroleptics or major tranquilizers,[1] are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. They are increasingly being used in the management of non-psychotic disorders but with serious side effects. Antipsychotics are usually effective in relieving symptoms of psychosis in the short term.
Risperidone, sold under the brand name Risperdal among others, is an antipsychotic
medical uses[edit]
Risperidone is mainly used for the treatment of schizophrenia, bipolar disorder, and irritability associated with autism.[9]
Risperidone seems to produce somewhat more extrapyramidal side effects and clearly more prolactin increase than most other atypical antipsychotics. It may also differ from other compounds in the occurrence of other adverse effects such as weight gain, metabolic problems, cardiac effects, sedation, and seizures. Nevertheless, the large proportion of participants leaving studies early and incomplete reporting of outcomes makes drawing firm conclusions difficult.[15]

Adverse effects[edit]
See also: List of adverse effects of risperidone
Common side effects include movement problems, sleepiness, dizziness, trouble seeing, constipation, and increased weight.[2][4] Serious side effects may include the potentially permanent movement disorder tardive dyskinesia, as well as neuroleptic malignant syndrome, an increased risk of suicide, and high blood sugar levels.[2][3] In older people with psychosis as a result of dementia, it may increase the risk of dying.[2]
While atypical antipsychotics appear to have a lower rate of movement problems as compared to typical antipsychotics, risperidone has a high risk of movement problems among the atypicals.[33][34] Atypical antipsychotics however are associated with a greater amount of weight gain.[34]

On 11 April 2012, Johnson & Johnson (J&J) and its subsidiary Janssen Pharmaceuticals Inc. were fined $1.2 billion by Judge Timothy Davis Fox of the Sixth Division of the Sixth Judicial Circuit of the U.S. state of Arkansas.[52] The jury found the companies had downplayed multiple risks associated with risperidone (Risperdal). The verdict was later reversed by the Arkansas State Supreme court.[53]
In August 2012, Johnson & Johnson agreed to pay $181 million to 36 U.S. states in order to settle claims that it had promoted risperidone and paliperidone for off-label uses including for dementia, anger management, and anxiety.[54]
In November 2013, J&J was fined $2.2 billion for illegally marketing risperidone for use in people with dementia.[55]
J&J has faced numerous civil lawsuits on behalf of children who were prescribed risperidone who grew breasts (a condition called gynecomastia); as of July 2016 there were about 1,500 cases in Pennsylvania state court in Philadelphia, and there had been a February 2015 verdict against J&J with $2.5 million awarded to a man from Alabama, a $1.75M verdict against J&J that November, and in 2016 a $70 million verdict against J&J.[56]
In 2015, Steven Brill posted a 15-part investigative journalism piece on J&J in Huffington Post, called "America's most admired lawbreaker", which was focused on J&J's marketing of risperidone.[57][58]
Brand names include Risperdal, Risperdal Consta, Risperdal M-Tab, Risperdal Quicklets, and Risperlet.

Risperdal Lawsuits status in 2019
There have been several lawsuits against the company ranging from lawsuits against them for the side effects of the drug to how Risperdal was marketed. They have also been brought up on criminal and civil charges.

Fines Against Risperdal Maker Settled for $2.2 Billion
Johnson and Johnson agreed to pay $2.2 Billion in criminal and civil fines after being accused by the U.S. Justice Department of illegally marketing the drug Risperdal. The drug company marketed it to older adults, children and developmentally disabled people.

About Risperdal
Risperdal, also sold under the generic name Risperidone, is an atypical antipsychotic drug prescribed to treat schizophrenia and the manic symptoms of bipolar disorder. It is manufactured by the Johnson and Johnson company in their Janssen division. The company had to pay billions of dollars already in Risperdal lawsuit verdicts and settlements in 2017 and before.
Below you can read more on the background of these cases and we give you options in case you experienced side effects yourself.
Records from the Philadelphia Court reveal that more than 3,000 new Risperdal lawsuits have been filed in the first quarter of 2017.

And.. it has not been the end of it for J&J this year, because according to a May 8th 2017 filing with the SEC, at least 16,900 Risperdal lawsuits are now pending in courts in the U.S. and Canada.
he state of Louisiana was seeking millions of dollars in fines, including reimbursement of public money that was used in purchasing Risperdal. The state had paid out more than $42 million for Risperdal prescriptions in 2003 and 2004. The state of Louisiana was awarded $258 million, a decision which has been overturned in 2014.

Over 10 states filed Risperdal lawsuits over illegal marketing tactics and other promotion practices for the drug. Other states are considering lawsuits as noted by documents filed by regulators in other states. Risperdal made over $4.5 billion in worldwide sales in 2007. Johnson and Johnson hadn’t set aside any money to pay for Risperdal lawsuits, which is a common practice for large corporations.
Risperdal Lawsuits
Authored by: Curtis Weyant, Managing Editor
Risperdal lawsuits allege patients weren’t warned of severe side effects like gynecomastia (abnormal breast tissue growth in males), type 2 diabetes, stroke and cardiac events. Patients have filed 14,000+ Risperdal lawsuits against Johnson & Johnson, but none have been settled yet. J&J was also fined $2.2 billion for off-label Risperdal marketing.
Risperdal Recall
In 2011, J&J and the FDA recalled the following medications: Risperdal tablets 3mg, Bottles of 60 Tablets (Lot #0GG904, expiration 5/2012) and risperidone tablets 2mg, Bottles of 60 Tablets (Lot #OlG175, expiration 8/2012). The drugs were recalled originally because of complaints about a foul odor. After the investigation, these products were found to be contaminated with TBA, a byproduct of a chemical preservative used on wood pallets.
$2.2 Billion Fine for Risperdal Off-Label Marketing
After a lengthy investigation, in 2012 the U.S. Department of Justice levied a $2.2 billion fine against Johnson & Johnson and its subsidiary Janssen Pharmaceuticals. The core reason for the fine was Janssen’s marketing and sale of Risperdal and other drugs (Invega and Natrecor) for unapproved uses, including the treatment of:
• Anxiety
• Agitation
• Confusion
• Depression
• Hostility
According to the DOJ’s public statement, the drug maker also had entered into an illegal kickback scheme with Omnicare Inc., a pharmacy that specializes in providing drugs to elderly care and assisted-living facilities. The $2.2 billion fine constitutes one of the largest healthcare-related fraud settlements in the history of the U.S. Even so, it is only a fraction of the $30 billion J&J had made from sales of Risperdal at the time of the settlement.
Risperdal Lawsuits Overview
• Associated Products
• Companies Involved
Johnson & Johnson
• Common Uses
To treat schizophrenia, bipolar I disorder, or irritability associated with autism
• How Many Lawsuits
• Major Side Effects
Gynecomastia, Hyperprolactinemia, Tardive Dyskinesia, Heart Attack
• Settlement Details
No Settlements
• Lawsuit Locations
State: CA, MO, PA

Common brand names: Risperdal, Risperdal M-Tab
Risperidone is used to treat certain mental/mood disorders.

Side Effects


Pregnancy category: Consult a doctor
Availability: Prescription needed
Drug classes: Antipsychotic · Atypical antipsychotic
Brand names: Risperdal · Risperdal M-Tab · Perseris · Risperdal Consta
May treat: Schizophrenia · Bipolar disorder · Autism · Dementia
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Risperdal® Lawsuit | Risperdal Lawyer, Attorney
UPDATE: Over 5,500 Risperdal Lawsuits in Philadelphia. ... Jury Awards $70 Million in 5th Risperdal Trial. In July 2016, a 16 year-old boy from Tennessee who grew female breasts after taking Risperdal was awarded $70 million by a jury in Philadelphia. He started growing breasts when he was 5 years old. ... Do I have a Risperdal Lawsuit?

Risperdal Settlement - Male Breasts Lawsuit & Compensation
• State of Texas v. Johnson & Johnson (2012)
• 36 States v. Johnson & Johnson (2012)
• Banks et Al v. Johnson & Johnson (2012)
• 77 Plaintiffs v. Johnson & Johnson (2013)
• U.S. Department of Justice v. Johnson & Johnson (2013)
• State of Montana v. Johnson & Johnson (2014)
• Pledger v. Johnson & Johnson (2015)
• State of South Carolina v. Johnson & Johnson (2015)
• Murray v. Johnson & Johnson (2015)
• Strange v. Johnson & Johnson (2015)
• Yount v. Johnson & Johnson (2016)
• Byrd v. Johnson & Johnson (2017)
• Have You Suffered from Severe Side Effects?
• In January 2012, Johnson & Johnson agreed to pay $158 million to settle a lawsuit filed by the State of Texas alleging that J&J illegally marketed Risperdal to state residents on Medicaid.After the settlement, Texas attorney general Greg Abbott stated: “Johnson & Johnson’s scheme to profit from the Medicaid program by overstating the safety and effectiveness of an expensive drug and improperly influencing officials ended up costing taxpayers millions of dollars.”
See more on

ADHD a fake disorder, neurologist-turned-author says
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• Richard Saul

By Cheryl K. Chumley - The Washington Times - Monday, January 6, 2014
Zero: That’s the percent of children suffering from attention deficit and hyperactivity disorder, a neurologist said in his new book, “ADHD Does Not Exist: The Truth About Attention Deficit and Hyperactivity Disorder.”
The book’s due out in February — and controversy is already generating, The New York Post reported.
Author Richard Saul said that over the course of his long career, and treatment of patients complaining of problems related to short attention spans and an inability to focus, he’s come to one conclusion: ADHD is only a collection of symptoms, not a disease or disorder in itself. It shouldn’t be listed as a separate disorder in the American Psychiatric Association’s Diagnostic and Statistical Manual, he said, The New York Post reported.
The number of ADHD diagnoses has increased in recent years simply because doctors are failing to probe deeply enough and question patients about related health matters — and because ADHD has become an embraced, accepted catch-all diagnosis, he said. And more bluntly: Mr. Saul said parents seek an easy way to get their children to sit down and shut up, and the treatments for ADHD — Adderall and Ritalian — do the trick.
But those drugs are dangerous and addictive stimulants, and they shouldn’t be prescribed so cavalierly, he said. For instance, one in nine children are now labeled as ADHD, and two thirds of them have been put on a stimulant, The New York Post reported.
“ADHD makes a great excuse,” Mr. Saul said, The New York Post reported. “The diagnosis can be an easy-to-reach-for crutch. Moreover, there’s an attractive element to an ADHD diagnosis, especially in adults. It can be exciting to think of oneself as involved in many things at once, rather than stuck in a boring rut.”

• goes by the generic name risperidone™
• contains the active ingredient risperidone
• was first approved in 1994 for schizophrenia, bipolar disorder
• is made by J&J subsidiary Janssen Pharmaceuticals
• has been the subject of several multi-billion-dollar lawsuits filed by state attorneys general*
Complaints about Risperdal
Complaints filed by state and federal officials and people injured by Risperdal charge that Janssen began promoting Risperdal for children as early as 1994. They also claim the drug maker illegally promoted Risperdal for a variety of off-label uses among elderly and pediatric patients, including ADHD (a fictitious “disease”), depression, Alzheimer’s, anxiety, obsessive compulsive disorder, post-traumatic stress disorder, conduct disorder.
Complaints also allege Johnson & Johnson planned an aggressive marketing campaign targeting doctors to prescribe Risperdal for unapproved purposes. The company:
• gave doctors thousands of free samples.
• created sales goals and incentives to motivate sales people to promote unapproved uses to elderly dementia patients and children with mental disabilities.
• paid kickbacks to the country’s largest pharmacy for nursing homes for promoting Risperdal to doctors treating nursing home patients.
• paid doctors to learn about the drug’s unapproved uses in a sham of a consulting program.
• gave doctors rewards like “lucrative consulting agreements,” speaker fees, and retreats at a luxury hotel to support unapproved uses and to increase their Risperdal prescriptions.
Risperdal captures Antipsychotic Drug Market
Johnson & Johnson’s aggressive, illegal marketing strategy helped Risperdal capture at least half of the dementia and pediatric markets for antipsychotics. But complaints allege the strategy was misleading, that it failed to disclose serious and potentially permanent side effects associated with use by elders and children.
FDA Warnings for Risperdal
In 2003 the FDA issued a strongly-worded warning letter to Johnson & Johnson announcing an increased risk of cerebrovascular adverse events for people taking Risperdal, including an increased risk of stroke in elderly patients. In 2004 the FDA sent another warning letter to healthcare professionals to announce an increased risk of hyperglycemia for Risperdal users. This condition can lead to serious complications such as ketoacidosis, diabetes, coma, even death.
2003 FDA Warning Letter to J&J, Janssen
The FDA told Johnson & Johnson that the company wrote physicians a false or misleading “Dear Healthcare Provider” letter on Nov. 10, 2003. FDA wrote that the letter violated Sections 502(a) and 201(n) of the Federal Food, Drug, and Cosmetic Act (Act) (21 U.S.C. 352(a) and 321(n)). The letter failed to disclose information “relating to hyperglycemia and diabetes mellitus to the approved product labeling (PI), minimizes the risk of hyperglycemia-related adverse events, which in extreme cases is associated with serious adverse events including ketoacidosis, hyperosmolar coma, and death, fails to recommend regular glucose control monitoring to identify diabetes mellitus as soon as possible, and misleadingly claims that Risperdal is safer than other atypical antipsychotics.”
FDA in April 2005 announced that patients with dementia-related psychosis treated with atypical (second generation) antipsychotic medications such as Risperdal increase their risk of dying compared with a placebo. FDA requested that the package insert for Risperdal be updated to include a black box warning to describe this risk and also noted Risperdal is not approved for this indication.
Risperdal causes Boys to Develop Breasts
Contraindications for Risperdal reports that Risperdal use is usually contraindicated for anyone with liver, kidney or heart disease, high blood pressure, heart rhythm problems; high cholesterol or triglycerides (certain fats in the blood); a history of heart attack, stroke or low white blood cell (WBC) counts; a history of breast cancer; seizures or epilepsy; diabetes (risperidone can increase blood sugar); a history of suicidal thoughts; Parkinson’s disease; or trouble swallowing.
Generic Risperdal
Johnson & Johnson’s Risperidone patent expired in 2004. Teva Pharmaceuticals then started to make and distribute a generic version of Risperdal. The only thing worse than brand name Risperdal might be the generic version of the drug.
Off-label Uses of Risperdal
Despite severe Risperdal “side effects,” some doctors prescribed it for:
• Generalized anxiety disorder
• Social Phobia
• Attention-deficit hyperactivity disorder
• No co-occuring disorders
• Bipolar Children
• Mentally retarded children
• Dementia
• Psychosis
• Agitation
• Depression
• Adjunctive treatment
• Eating disorders
• Insomnia
• Obsessive-compulsive disorder
• Augmentation with SSRI
• Augmentation of citalopram
• Personality disorder
• Borderline personality disorder
• Schizotypal personality disorder
• Post-traumatic stress disorder
• Moderate or high evidence of efficacy
• Substance abuse (Alcohol, Cocaine, Methamphetamine, Methadone)
• Tourette’s syndrome
Risperdal Side Effects
Risperdal side effects range from minor to severe. More than ten percent of Risperdal patients have reported side effects that include headaches, sleeping problems, tremors. Other Risperdal patients may experience back pain, blurred vision, coughing, dizziness, fever, indigestion, and many more side effects. Rispersal Side Effects include:
• aggressive behavior
• agitation
• anxiety
• changes in vision
• decreased sexual desire or performance
• difficulty concentrating
• difficulty speaking or swallowing
• inability to move the eyes
• loss of balance control
• mask-like face
• memory problems
• menstrual changes
• muscle spasms of the face, neck, and back
• problems with urination or increase in the amount of urine
• restlessness or need to keep moving (severe)
• shuffling walk
• skin rash or itching
• stiffness or weakness of the arms or legs
• tic-like or twitching movements
• trembling and shaking of the fingers and hands
• trouble sleeping
• twisting body movements
More Risperdal Side Effects
Other Risperdal side effects include back pain, chest pain, speech or vision problems, sudden weakness or numbness in the face, arms, or legs, unusual secretion of milk, confusion, dizziness, drowsiness, extreme thirst, fast or shallow breathing, fast and weak heartbeat, headache, increased thirst, lip smacking or puckering, loss of appetite, muscle cramps, pale, clammy skin, poor coordination, prolonged and painful and inappropriate erection of the penis, puffing of the cheeks, rapid or worm-like movements of the tongue, shivering, talking and acting with uncontrollable excitement, uncontrolled twisting movements of neck, trunk, arms, or legs, unusual bleeding or bruising,unusual facial expressions or body positions.
FDA Alerts for Risperdal
FDA Drug Safety Communication included a warning in June 2011 of Medication errors resulting from confusion between risperidone (Risperdal) and ropinirole (Requip). FDA alerted the public “to medication error reports in which patients were given risperidone (Risperdal) instead of ropinirole (Requip) and vice versa. In some cases, patients who took the wrong medication needed to be hospitalized.” See this link: Risperdal confused with Requip.
Advice to 18-Year-Old with Gynecomastia
Risperdal Medication Guide & Resources
• Food and Drug Administration
• FDA Alert for Risperdal 2006
• Prolactin Levels, Adverse Events with Risperdone
• Predominant role of 9-hydroxy metabolite
• Anti-psychotic Medication in Children, Adolescents
• Prolactin, hyperprolactinaemia, antipsychotic treatment
• Risperdal Lawsuit Consultation
Risperdal Settlements and Legal Fines
Janssen Pharmaceuticals, Inc. has plead guilty and been fined millions of dollars to resolve allegations of misbranding and filing false claims for its schizophrenia drug Risperdal.
• FDA News: J & J pleads guilty, will pay $1.6 Billion in fines
• Johnson & Jonson fined $1.1 Billion for Risperdal promotion
• J & J to pay $2 Billion in Risperdal Settlement
• Johnson & Johnson will pay $181 Million to settle Risperdal Ad Claims
Risperdal Lawsuit Information
If you or a loved one has experienced adverse side effects from the use of Risperdal, you may qualify for compensation to help with the cost of your medical expenses, as well as your pain and suffering. To contact a Risperdal lawyer for a free legal consultation and Risperdal lawsuit information, call Matthews and Associates toll free at 1-888-520-5202 or email us now.
• First Risperdal Verdict $2.5 Million
• J&J fined $2.2 Billion for Risperdal Marketing
• Risperdal Lawsuits – Fraud & Settlement News
• Risperdal Lawsuit Documents could be sealed
• Risperdal Lawsuit Lawyer
Please peruse our testimonials to see how we have helped others.
* U.S. Government prosecutors alleged that Johnson & Johnson promoted Risperdal for boys suffering from mental disabilities despite knowing that the drug could raise levels of a hormone known to stimulate the development of breasts.
I can't say enough good things about the service I received from Matthews & Associates. They should be highly commended for their efficiency, expertise, and comprehensive knowledge. (Their) demeanor and hard work have completely changed my view and perception of attorneys.

— Meryl L. of California

Olanzapine: Uses vs Side Effects
Why is this medication prescribed? Olanzapine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older. It is also used to treat bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods) in adults and teenagers 13 years of age and older. Olanzapine is in a class of medications called atypical antipsychotics.
Olanzapine: MedlinePlus Drug Information
In Summary. Commonly reported side effects of olanzapine include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinesia, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia.
Olanzapine Side Effects in Detail -

Haloperidol: Uses vs Side Effects
It can decrease negative thoughts and hallucinations . Haloperidol can also be used to treat uncontrolled movements and outbursts of words/sounds related to Tourette's disorder . Haloperidol is also used for severe behavior problems in hyperactive children when other treatments or medications have not worked. Haloperidol is a psychiatric medication (antipsychotic-type) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).
Haloperidol Oral : Uses, Side Effects, Interactions ...
Common side effects of Haldol include nausea, vomiting, diarrhea, dry mouth, nervousness, headache, dizziness, spinning sensation, drowsiness, sleep problems (insomnia), restlessness, anxiety, skin rash, itching, spontaneous eye movements, mood changes, breast enlargement, irregular menstrual periods, loss of interest in sex, blurred vision, ...
Common Side Effects of Haldol (Haloperidol Injection) Drug ...

Professional Lorazepam is a federal controlled substance (C-IV) because it can be abused or lead to …

Lorazepam: Uses vs Side Effects
This medication is used to treat anxiety. Lorazepam belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. This drug works by enhancing the effects of a certain natural chemical in the body (GABA).
Common side effects may include: dizziness, drowsiness; weakness; slurred speech, lack of balance or coordination; memory problems; or feeling unsteady.
Ativan (lorazepam) drug - patient side effects and images

Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death (see WARNINGS; PRECAUTIONS, Clinically Significant Drug Interactions).
• Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate.
• Limit dosages and durations to the minimum required.
• Follow patients for signs and symptoms of respiratory depression and sedation.

Class Action Lawsuit Against Manufacturers of Celexa, Prozac, Zoloft, Effexor, Lexapro, Paxil, Seroquel and Ativan

Jennifer Gordon 684 Comments
Scores of lawsuits have been launched against the pharmaceutical giants and numerous medical studies have proven that the antidepressant, antipsychotic and benzodiazepine drugs which they are producing are causing significant harm to the patients who have been prescribed them.

If you have suffered from any of the following side effects of SSRI antidepressants, such as Celexa, Prozac, Zoloft, Effexor, Lexapro and Paxil, antipsychotic medications, such as risperidone, quetiapine (Seroquel) and ziprasidone or benzodiazepines, such as alprazolam, bromazepam, lorazepam (Ativan) and diazepam, please sign up for a class action lawsuit that will be launched against the manufacturers of these deadly drugs:

Memory impairment
Mental impairment
Memory loss
Sexual dysfunction
Depersonalization (feeling that you are separated from yourself)
Derealization (feeling that you are separated from the rest of the world)
Visual and/or auditory hallucinations
Self-destructive behaviour
Obsessive Compulsive Disorder
Impulse Control Disorder
Mood swings
Weight gain/puffiness
Bizarre or criminal acts
Social phobia
Reckless spending
Compulsive lying
No concern for consequences of actions
Impaired judgement
Suicidal thoughts
Tardive dyskinesia

We need to make the drug companies pay for the lives they have destroyed. We also need to raise awareness of the dangers associated with taking antidepressants, antipsychotics and benzodiazepines; drugs which are prescribed to millions of people. How many more lives will be ruined and lost if we don't act? The more names I'm able to collect on this petition, the greater the chance of success we will have when launching a class action lawsuit. This is my driving ambition in life. I know of a number of wonderful people who are no longer alive because of these drugs. If you are suffering, my heart goes out to you. Please help me to put a stop to this crime against humanity. Thank you!

Effects of long-term benzodiazepine use
• The effects of long-term benzodiazepine use include drug dependence and neurotoxicity as well as the possibility of adverse effects on cognitive function, physical health, and mental health. Benzodiazepines are generally effective when used therapeutically in the short term, but even …

Rapid withdrawal and misprescribing of a benzodiazepine leads to £1.35m settlement for Luke Montagu, CEP co-founder
By admin on 18/07/2015 in In the Press, News, Psychiatric drugs, Recovery Stories : Benzodiazepine Litigation
BENZODIAZEPINE LITIGATION. LATEST SUCCESSFUL COMPENSATION CLAIMS • Diazepam, Oxazepam, Lorazepam, Temazepam and other benzodiazepines…involuntary addiction, Caroline Moore, December 14, 2015. BENZODIAZEPINE LITIGATION IN THE NEWS • Misprescribing of a benzo leads to £1.35m settlement for Luke Montagu, Council for Evidence-Based Psychiatry,...

CLASS ACTION LAWSUIT. In the 1980s and early 1990s, benzodiazepines were responsible for the largest-ever class-action lawsuit against drug manufacturers in the UK. The lawsuit involved 14,000 patients and 1,800 law firms and over £50 million pounds …

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